Evaluasi Sediaan Krim Ekstrak Etanol Daun Tapak Dara (Catharanthus roseus L.) Sebagai Tabir Surya dalam Menghambat Pembentukan Eritema

Sunlight is composed of visible and ultraviolet light, but only 10% the UV can penetrate Earth's atmosphere. Exposure to UV-B on human skin result in sunburn erythema. To avoid damage from UV, sunscreens containing oxybenzone octinoxate compounds are used. However, these have adverse effects skin, so finding a more natural alternative essential. Phenolic flavonoids, which found plants, believed serve as protect erythema caused by exposure. The objective this study was assess efficacy tapak daura leaf extract cream sunscreen prevent mice. made using maceration method with 96% ethanol 1:4 ratio. Three formulations were created 1%, 1.5%, 3% concentrations extract, respectively. Formulation F0 did not include extract. creams then tested mouse exposed for eight hours. results demonstrated that could against rays reducing number spots F3 group 6.3 two.